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Dr Connor Sharp

Dr Connor Sharp portrait

Areas of interest

Connor's research focusses on the mechanisms bacteria use to compete with each other, and how we can use these mechanisms to prevent or treat infection.

His current projects include:
The interplay between bacterial warfare and nutrient competition in the microbiome
The evolution of resistance to protein antimicrobials
Optimising protein antimicrobial treatment using experimental evolution
Discovery of novel candidate antibiotics using bioinformatics

Research Centres and groups
National Collaborators
Prof Kevin Foster – University of Oxford
International collaborators
Dr Olivier Cunrath – University of Strasbourg
Dr Sean Booth – University of Manitoba

Teaching

  • Part 2: Infectious Diseases, The Bacterial Cell
  • Part 3: Pathogens

Background

2009-2013: BSc Molecular Biology University of Exeter

2013-2017: DPhil Biochemistry, University of Oxford

2017-2023: Postdoctoral research associate, University of Oxford

2024-present: Lecturer in Biomedical Science, University of Reading

Selected publications

Sharp C, Foster KR (2022) Host control and the evolution of cooperation in host microbiomes. Nature Communications

Atanaskovic I, Sharp C, Press C, Kaminska R, Kleanthous C. (2022) Bacterial Competition Systems Share a Domain Required for Inner Membrane Transport of the Bacteriocin Pyocin G from Pseudomonas aeruginosa mBio. ASM Journals

Sharp C, Boinett C, Cain A, Housden NG, Kumar S, Turner K, Parkhill J, Kleanthous C. (2019) O-Antigen-Dependent Colicin Insensitivity of Uropathogenic Escherichia coli. Journal of Bacteriology

Publications

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